Biofloxavet® C for Local Infections Treatment Cat (enrofloxacin 15mg) 20 tablets
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Biofloxavet® C for Local Infections Treatment Cat 20 tablets
1. NAME OF THE MARKETING AUTHORISATION HOLDER
2. NAME OF THE VETERINARY MEDICINAL PRODUCT
Content Biofloxavet® C
Enrofloxacin 15 mg Excipients Each tablet
The product contains as excipients: lactose, wheat starch, hydroxypropylcellulose, microcrystalline cellulose, magnesium stearate and colloidal silica.
Enrofloxacin is a synthetic broad-spectrum chemotherapeutic of the fluoroquinolones group.
Owing to the inhibition of the bacterial DNA-gyrase it causes a potent bactericidal effect against
Gram-negative, a wide range of Gram-positive bacteria and Mycoplasma spp. It is inactive
against anaerobic microorganisms. It is very well distributed in the tissues, possesses bactericidal
activity in small tissue concentrations, and is well tolerated by animals.
After oral administration of Biofloxavet® C tablet to cats and Biofloxavet® D tablets for dogs at a
dose of 5 mg enrofloxacin per kg b.w., enrofloxacin and absorbs quickly and almost completely
by the digestive tract thereby creating within a short period of time antimicrobial plasma
concentrations of enrofloxacin and its active metabolite ciprofloxacin higher than the MIC for
clinically important microbial agents which are maintained for 24 hours after the administration.
Enrofloxacin is well distributed within the organisms of cats. Its elimination from the organism
is primarily via the urine and bile/faeces.
For treatment of local and systemic infections in cats and dogs, caused by Gram-positive
bacteria: Staphylococcus and Streptococcus, Gram-negative bacteria: E.coli, Salmonella spp.,
Klebsiella spp., Proteus spp., Pseudomonas spp., Pasteurella spp., Haemophilus spp. as well as
Mycoplasma spp. – in primary and secondary infections of the gastrointestinal, respiratory and
urogenital systems; in skin, wound infections and infections of the external acoustic canal.
Do not administer to pregnant and growing animals until the completion of the growth.
Do not give to pregnant and lactating animals.
MODE OF ADMINISTRATION
Biofloxavet C for cats
The daily dose is 1 tablet per 3 kg body weight (=5 mg/kg b.w.), administered a single time or divided into two portions given at 12-hour interval.
A 3 to 5-day therapeutic course is normally sufficient but in case of severer infections the duration of treatment may be extended to 10 consecutive days.
On rare occasions, transitional gastrointestinal disorders may occur.
In the original container in warehouse facilities protected from direct sunlight.
Keep out of the reach and sight of children.
Cardboard box of 2 blisters with 10 tablets each.
Do not eat, drink or smoke while handling the product. After use, wash hands with water and
Do not administer simultaneously with theophylline and non-steroidal anti-inflammatory drugs.
Substances containing magnesium and aluminum may decrease the absorption of enrofloxacin.
The simultaneous administration of enrofloxacin with chloramphenicol, tetracycline and
macrolides can result in an antagonistic effect.
The signs of acute toxicity may be referred to the neurointoxications – ataxia, tremor, tonic
convulsions, lethargy, dyspnea, ventral decubitus.