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ENDECTOVET for big Dogs Dewormer Heartworm (Dirofilaria immitis) 4 tab. One tablet per 50 kg body weight

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ENDECTOVET for big Dogs Dewormer Heartworm (Dirofilaria immitis) 4 tab. One tablet per 50 kg body weight

ENDECTOVET for use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days)

One tablet per 50 kg body weight.

 

 

 

 

 

1. NAME  OF THE MARKETING AUTHORISATION HOLDER

 

Name: Biovet JSC

 

2. NAME OF THE VETERINARY MEDICINAL PRODUCT

ENDECTOVET

 

 

COMPOSITION

Doramectin 0.125 mg

Doramectin 0.250 mg

Doramectin 1.250 mg

 

INDICATIONS

For use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days).

 

CONTRAINDICATIONS

Do not administer to dogs of Collie, Shelti and Bobtail breeds, as well as to puppies below 6 weeks of age. 

 

AFFECTED BREEDS

 

Approximately three of every four Collies in the United States have the mutant MDR1 gene. The frequency is about the same in France and Australia, so it is likely that most Collies worldwide have the mutation. The MDR1 mutation has also been found in Shetland Sheepdogs (Shelties). Australian Shepherds, Old English Sheepdogs, English Shepherds, German Shepherds, Long-haired Whippets, Silken Windhounds, and a variety of mixed breed dogs.

 

The only way to know if an individual dog has the mutant MDR1 gene is to have the dog tested. As more dogs are tested, more breeds will probably be added to the list of affected breeds.

Breeds affected by the MDR1 mutation (frequency %)

Breed Approximate Frequency

Australian Shepherd 50%

Australian Shepherd, Mini 50%

Border Collie < 5%

Collie 70 %

English Shepherd 15 %

German Shepherd 10 %

Herding Breed Cross 10 %

Long-haired Whippet 65 %

McNab 30 %

Mixed Breed 5 %

Old English Sheepdog 5 %

Shetland Sheepdog 15 %

Silken Windhound 30 %

           

MODE OF ADMINISTRATION

Prescription only.

Orally, with non-liquid feed.

 

DOSAGE

Administration/dosage:

 

For oral administration with some attractive food or  put the tablet in the back of the dog throat, close its mouth and hold the nose up. Blowing slightly to the pet's nose may encourage swallowing.

 

Relative dose – 0,025 mg/kg body weight

 

Body weight, kg

Weight of tablet, mg

Content of  Doramectin  per the tablet, mg

Frequency of application

5

50

0,125

monthly

10

100

0,250

monthly

50

500

1,250

monthly

 

One tablet per 50 kg body weight. The treatment may be repeated after a month. In cases of flea infestation the living premises must also be disinfected.

 

Endectovet tablets should be administered monthly. The application starts a month before the flight mosquitoes and stops one month after that. If the interval between applications is more than 30 days, the efficacy of doramectin may decrease. To optimize the effectiveness of the product, the tablets must be administered on the same day of the month. When the dog was taking other product for control Dirofilaria immitis (heartworm), the application of  Endectovet tablets must be no earlier than one month after the last treatment.

 

To avoid resistance and ineffective treatment, avoid the following:

- Too frequent and repeated use of anthelmintics from the same class, for an extended period of time;

- Using lower doses than recommended;

 

If in doubt about the emergence of resistance should be make further research.

 

STORAGE

In the original container, well closed, in dry facilities, protected from direct sunlight at temperature between 15 and 30°C.

 

WARNING

Keep out of the reach of children!

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